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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
34.85
Human Site:
Y289
Identified Species:
58.97
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
Y289
P
T
E
P
V
T
D
Y
R
T
A
V
S
G
I
Chimpanzee
Pan troglodytes
XP_528522
404
44489
Y271
P
T
E
P
V
T
D
Y
R
T
A
V
S
G
I
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
Y289
P
T
E
P
V
T
D
Y
R
T
A
V
S
G
I
Dog
Lupus familis
XP_548392
428
46939
Y291
P
T
Q
P
V
T
D
Y
R
T
A
V
S
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
Y299
P
T
E
P
V
T
D
Y
R
T
A
V
S
G
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
Y307
P
T
E
K
V
T
D
Y
R
T
T
V
S
G
I
Chicken
Gallus gallus
XP_001236410
416
45873
Y288
P
T
E
E
V
T
D
Y
R
T
A
V
S
G
I
Frog
Xenopus laevis
Q91560
421
46679
Y280
P
T
E
R
V
T
D
Y
R
T
A
V
S
G
I
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
Y279
P
T
E
K
V
T
D
Y
R
T
A
V
S
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
A184
E
I
V
Q
K
E
V
A
E
I
L
R
G
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
E252
L
F
K
G
N
A
E
E
F
L
T
V
Q
K
E
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
D180
L
L
G
H
P
K
K
D
L
R
D
T
S
E
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
I195
A
Q
K
K
T
A
D
I
L
E
G
R
I
L
V
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
W262
P
T
A
F
V
T
D
W
R
T
H
V
S
G
I
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
86.6
93.3
93.3
93.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
93.3
93.3
93.3
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
73.3
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
20
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
15
0
8
0
0
58
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
79
8
0
0
8
0
0
0
0
% D
% Glu:
8
0
58
8
0
8
8
8
8
8
0
0
0
8
8
% E
% Phe:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
8
0
8
72
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
79
% I
% Lys:
0
0
15
22
8
8
8
0
0
0
0
0
0
8
0
% K
% Leu:
15
8
0
0
0
0
0
0
15
8
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
72
0
0
36
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
72
8
0
15
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% S
% Thr:
0
72
0
0
8
72
0
0
0
72
15
8
0
0
0
% T
% Val:
0
0
8
0
72
0
8
0
0
0
0
79
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _